Fraxinus: a Facebook game to crowdsource the fight against ash dieback disease HD

Please share and embed this video with credit to BBSRC. See full press release here: http://bit.ly/14Gxc2u Let scientists keep the lab coat, goggles and pipe…
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Greenpeace’s one-of-a-kind new flagship ship, the Rainbow Warrior, is in Seattle this weekend for free public tours. The 3o million dollar paid for by crowd …

  1. bbsrcmedia
    bbsrcmedia says:

    Hi, so you take the target pattern and the sequence and look at how the two
    are currently aligned. For every matched pair you get 1 point (so you can
    get a maximum number of points equal to the length of the target pattern.)
    For every mismatched one you lose 3pts. You lose 5pts for inserting a gap,
    and lose 2pts for extending an existing gap. All points for all sequences
    in the display are summed to give you the total score. Hence >1000pt scores
    when doing well and negative when doing badly.

  2. Arran Frood
    Arran Frood says:

    Nice video on the new Fraxinus game for Facebook: real scientific problems
    tackled using a crowdsourcing approach and real data for gaming. Please
    share this video (if you like it ;-)

  3. Spidra Webster
    Spidra Webster says:

    “In December 2012, scientists from The Sainsbury Laboratory hired
    Sheffield-based gaming company Team Cooper to develop ‘Fraxinus’. The game
    uses real genetic data from the fungus which causes Chalara ash dieback and
    from the common ash, Fraxinus excelsior.

    It involves matching and rearranging patterns of coloured leaf shapes which
    represent nucleotides – the letters that make up a genome sequence. People
    are better at this than computers alone, because the human eye can
    recognise patterns that computers miss.

    The Facebook game is part of a rapid response to ask dieback funded by the
    Biotechnology and Biological Sciences Research Council (BBSRC), which
    includes understanding more about the disease, how it attacks ash trees,
    finding natural resistance and predicting and mitigating disease
    progression.”

  4. Arran Frood
    Arran Frood says:

    Fraxinus game now played in more than 80 countries since launch this week.
    See this 5min video to see how gaming and crowdsourcing can advance
    research to tackle diseases….

  5. bbsrcmedia
    bbsrcmedia says:

    Hi pmcleod999, indeed there is a paper that explains the theory behind how
    projects like this work. We can post links here, but if you search for
    ‘Phylo: A Citizen Science Approach for Improving Multiple Sequence
    Alignment’ that has info on how puzzle games like Fraxinus (in this case
    the Phylo game) use games for the MSAs (multiple sequence alignments).
    doi:10.1371/journal.pone.0031362 . Given time we’re sure there will be one
    specific to Fraxinus.

  6. bbsrcmedia
    bbsrcmedia says:

    Hi LaAttiDah, some notes from the game-makers: As in many puzzle games
    Fraxinus is open-ended with respect to strategy; it provides the rules and
    you provide the brains and solutions. Match as many or as few as you think
    you need to. You can also delete or leave the odd colours to win. Only by
    scoring higher can you claim the pattern. The game was widely tested
    including school-age children (as in the video), so its pitched at all
    ages. Thanks for the time you’ve invested already.

  7. bbsrcmedia
    bbsrcmedia says:

    Hi Smiffy, alas, at present the game is only available on desktops and
    laptops. This isn’t an oversight, more that the scientists had a limited
    time and budget to get things going (and time is of the essence with the
    ash dieback problem) and so there’s no mobile version at present.

  8. TheBobdoctor
    TheBobdoctor says:

    Not enough of an explanation as to what is required. What does the x mean
    and the exclamation mark.? Let us see someone playing with comments without
    the music.

  9. LaAttiDah
    LaAttiDah says:

    1. NPR report told me about the game 2. I do not understand the game. 3.
    The instructions did not explain the 25 rows of colors, do I have to match
    all 25 rows? 3. do I delete ever odd color to claim a pattern 4. do I leave
    the gaps 5. do I squished the colors together 6. what about all the left
    over colors 7. should beta-test with non-gamers and grandmothers to make
    the instructions more clear 8. after 2 hours trying to help out, which I
    really want to do, I may give up like 100’s of others.

  10. bbsrcmedia
    bbsrcmedia says:

    Hi TheBobdoctor, thanks for your feedback on the video, which we do take
    into account. The best way to find out more about the game is to give it a
    go: here’s the link: apps.facebook.com/fraxinusgame/ As i recall, the X and
    ! mean deletions and additions to reads you play with compared to the
    reference pattern. In making the video, we did try and include more about
    the game but it all got too long. We also specifically turned the music
    down then off when the game explanation starts.

  11. bbsrcmedia
    bbsrcmedia says:

    The Fraxinus game community on Facebook might also help: facebook.com/
    fraxinusgame Personally, i found going over the in-game tutorial again
    helped me get my head around it more. On your Qs 3. You have to TRY to
    match all rows (but not all); 3-6. You can leave gaps,spaces and move
    colours as necessary and this all affects your matching score. 7. It was
    widely tested. 8. Don’t give up! Have fun and hope it works out…

  12. pmcleod999
    pmcleod999 says:

    PS. I did check the links in the description. Just looking for something a
    little more in depth. Thanks

  13. Rochelle Treister
    Rochelle Treister says:

    Please explain how the scoring works. Sometimes if I delete one gene and
    create a space, my score goes up;sometimes it goes down. It would help to
    understand how the scoring algorithm is calculated.

  14. pmcleod999
    pmcleod999 says:

    Loved phylo and love this! This concept should be applied to moar problems
    😀 Will point this one out to all my friends in biotech!! Is there an info
    page or a free access paper which explains exactly how this project works?
    I assume its manually performing MSAs but what do all the individual
    “reeds” represent? All I heard was DNA samples, do they represent closely
    related analogues? Keep up the brilliant work!